ResearchGate |
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Research and application of conductive nanofiber nerve guidance conduits for peripheral nerve regeneration: a narrative review |
Autologous nerve grafting has long been considered the gold standard treatment for repairing peripheral nerve injury. However, it faces challenges such as limited availability of donor nerves and complications at the donor site. As a result, there has been an ongoing shift toward the use of novel biomaterials. Conductive nanofiber nerve guidance conduits appear to be an optimal solution due to their excellent mechanical stability, nanofiber structure, and electrical stimulation properties, which can help restore the original neural microenvironment. This review article focuses on an in-depth investigation of breakthroughs in conductive nanofiber nerve guidance conduits for peripheral nerve |
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2025-02-01 Read more about this article in source |
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A comparative fractographic analysis for the effect of polymeric nanofiber reinforcements on the tensile behavior of multi-layered epoxy nanocomposites
This study presents a comparative investigation into the effects of four different nanofibers—PA66, PStX, PAN, and PVB—on the mechanical performance and failure mechanisms of epoxy adhesive films. These nanofiber‐reinforced adhesive layers were manufactured via a dry‐reinforcement resin film infusion method and tested under uniaxial tensile loading. Mechanical results showed that PA66 and PStX nanofibers improved tensile strength by up to 25%, primarily by mitigating crack initiation at free edges and promoting effective fiber–matrix bonding. In contrast, PAN nanofibers induced micro‐cracks at the fiber–resin interface, amplifying crack coalescence and reducing strength by 25%. 03/01/2025