Modular Coatings Steer Nanoparticles Toward Specific Organs in Mice in ssalimpour

Salimpour Website |Researchers developed modular organ-targeting metal-phenolic network coatings that altered where diverse nanoparticles accumulated after intravenous administration in mice. By tuning metal ions, phenolic ligands, and PEG molecular weight, the researchers redirected nanoparticles

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Modular Coatings Steer Nanoparticles Toward Specific Organs in Mice

Modular Coatings Steer Nanoparticles Toward Specific Organs in Mice

Researchers developed modular organ-targeting metal-phenolic network coatings that altered where diverse nanoparticles accumulated after intravenous administration in mice. By tuning metal ions, phenolic ligands, and PEG molecular weight, the researchers redirected nanoparticles toward the lungs, kidneys, heart, and brain while preserving functional mRNA delivery in coated lipid nanoparticles.