Advances in Electrospun Nanofibers: Versatile Materials and Diverse Biomedical Applications at Salimpour Site.

In this study, a cryogel/nanofiber hybrid material was developed using a new lotus-leaf-inspired strategy. The lotus effect was generated via beaded poly( ε -caprolactone) (PCL) nanofibers produced from the 9 wt% PCL solution with low viscosity and high surface tension via electrospinning. A poly(hydroxyethyl methacrylate) (PHEMA) cryogel layer was constructed through polymerization onto the beaded PCL nanofibrous mat. The thickness of the PHEMA cryogel/beaded PCL nanofiber hybrid material was 3.19 ± 0.07 mm. Morphological characterization studies of the hybrid material were conducted by scanning electron microscopy (SEM). The mean diameter of the beaded PCL nanofibers was 97.22 ± 21.18 nm. 2024-03-01

As the global facial mask market continues to grow, consumers have put forward higher requirements for the functionality and ingredients of mask products. Ordinary facial masks mostly use ordinary non-woven fabrics as the mask base fabric and are used with essence. Preservatives are generally added. At the same time, they are susceptible to the influence of the external environment and are easily oxidized, causing the mask to deteriorate and cause skin allergic reactions. In addition, traditional facial masks have problems such as poor fit with the skin, poor breathability, insufficient absorption of nutrient solutions, and easy dripping. 2024-06-01

The field of drug delivery has seen remarkable advancements with the advent of nanofiber technology, offering promising solutions to longstanding challenges in therapeutic administration. Nanofibers, characterized by their high surface area-to-volume ratio, porosity, and mechanical strength, provide an exceptional platform for innovative drug delivery systems. This abstract explores the multifaceted applications of nanofiber technology in drug delivery, highlighting their ability to enhance drug stability, bio-availability, and controlled release profiles. By utilizing various drug loading techniques such as physical adsorption, chemical conjugation, and encapsulation, 2024-07-01

The nanofiber materials of three-dimensional spatial structure synthesized by electrospun have the characteristics of high porosity, high specific surface area, and high similarity to the natural extracellular matrix (ECM) of the human body. These are beneficial for absorbing wound exudate, effectively blocking the invasion of external bacteria, and promoting cell respiration and proliferation, which provides an ideal microenvironment for wound healing. Moreover, electrospun nanofiber dressings can flexibly load drugs according to the condition of the wound, further promoting wound healing. Recently, electrospun nanofiber materials have shown promising application prospects as medical 2024-09-01

Autologous nerve grafting has long been considered the gold standard treatment for repairing peripheral nerve injury. However, it faces challenges such as limited availability of donor nerves and complications at the donor site. As a result, there has been an ongoing shift toward the use of novel biomaterials. Conductive nanofiber nerve guidance conduits appear to be an optimal solution due to their excellent mechanical stability, nanofiber structure, and electrical stimulation properties, which can help restore the original neural microenvironment. This review article focuses on an in-depth investigation of breakthroughs in conductive nanofiber nerve guidance conduits for peripheral nerve 2025-02-01