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Drug delivery system overcomes circulatory roadblock that prevents gene therapies from reaching their targets |
Exploiting the remarkable capability of viruses to transport gene therapies past what until now has been a circulatory roadblock is at the heart of a University of Alberta-led discovery that promises to re-energize the field ... |
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2024-10-24 Read more about this article in source |
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Diabetic ulcer is a prevalent complication affecting a large number of individuals globally and presents a significant challenge in healthcare, often... 10/29/2026
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Plant biomass is a sustainable resource created by absorbing and fixing carbon dioxide from the atmosphere. The basic unit of cells is made up of... 10/29/2026
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The properties of produced nanofibers are normally too small to be observed with the naked eye. Therefore, advanced equipment is necessary to... 10/29/2026
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The growing demand for sensitive, rapid, and reliable analytical techniques for human health and environmental monitoring has driven the development... 10/29/2026
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Electrospun nanofiber membranes are innovative materials produced through electrospinning process, a technique that generates ultrathin fibers from... 10/29/2026
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Cells naturally send tiny packages to one another to share information. Researchers at Carnegie Mellon University have developed a simple, low-cost way to turn those packages into drug carriers that can deliver treatments ... 10/28/2026
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Hybrid Immune-Cell Nanoparticles Reduce Inflammation and Bone Loss in Periodontitis
Researchers developed NMm@MINO, a minocycline-loaded gelatin nanoparticle coated with hybrid neutrophil–macrophage membranes to tackle bacterial infection, inflammation, and periodontal tissue damage. In laboratory and rat experiments, the platform killed bacteria, altered inflammatory responses, promoted osteogenesis-associated processes, suppressed osteoclast activity, and reduced alveolar bone loss. 10/28/2026
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Engineered albumin helps a therapeutic protein last longer and cross mucosal barriers
Protein-based medicines have transformed the treatment of many diseases, but they often come with a limitation: they must be injected, sometimes repeatedly, because they are rapidly cleared from the bloodstream. For patients ... 10/28/2026
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Computational model extends the study of nanostructures beyond classic layered systems
Since the production of graphene in 2004, two-dimensional materials have been sparking scientific and technological interest. As they are only a few atomic layers thick, or even just a single atomic layer, they can exhibit ... 10/28/2026
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Researchers at the Nano Life Science Institute (WPI-NanoLSI) at Kanazawa University have discovered that tiny structural defects can trigger the breakdown of microtubules, the microscopic structures that help cells maintain ... 10/27/2026
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Researchers used spark plasma sintering technology to deposit silver, zinc, and copper metal oxide nanoparticles directly onto thermoplastic starch/carboxymethyl cellulose films, then measured changes in mechanical strength, wettability, morphology, color, and thermal behavior. The treatment increased tensile strength and reduced surface wettability, with the results varying by metal and reflecting interactions between the deposited particles and polymer functional groups. 10/27/2026
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Dual-Target Nanoparticles Reprogram Macrophages and Improve Survival in Experimental Sepsis
Researchers developed glutathione-responsive EONPs that co-deliver STING and DHODH inhibitors to reprogram macrophage inflammatory metabolism in experimental sepsis. In mouse models, the treatment reduced inflammation and organ injury, improved short-term survival, and altered gut microbial metabolism, with 5-HIAA contributing to the immune response. 10/26/2026
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Researchers developed diimmonium DB·2X nano-agents that support photoacoustic imaging at 1700 nm, with DB·2TFSI showing strong performance in preclinical imaging experiments. In mouse models, 1700 nm imaging reduced endogenous background interference and improved signal-to-background ratios compared with 1064 nm, supporting further investigation of NIR-IIb photoacoustic contrast agents. 10/26/2026
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Researchers developed a rapid, one-pot method that used sunlight and a commercial vincristine formulation to form gold nanoparticles within five minutes without separate reducing or stabilizing agents. The particles retained vincristine’s antiproliferative activity against Colo-205 colon cancer cells and showed greater DPPH radical scavenging than free vincristine at several tested concentrations, while questions about drug photostability, release, stability, and in vivo performance remain. 10/22/2026
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Nanotechnology could help crops withstand drought through nanoparticles, nanobubble irrigation, water-retaining hydrogels, and nanosensors, but challenges remain. 10/08/2026
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Structure-Property Relationship of Electroplated Cu Film by Combining Electron Backscatter Diffraction (EBSD) and High-Speed Nanoindentation Techniques
High-speed nanoindentation and EBSD techniques are employed to analyze self-annealed electroplated Cu, highlighting spatial variations in mechanical properties. 10/06/2026
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Researchers are exploring whether engineered nanocarriers can improve delivery of drugs, genes, and RNA-based therapies to specific lung cells while reducing unwanted effects elsewhere in the body. 09/29/2026
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Developing stretchable displays integrates quantum dot engineering and novel printing methods, addressing key challenges in performance and durability. 09/25/2026
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NanoLabSizer revolutionizes nanoparticle sizing with SR-DLS, enabling fast, non-destructive measurements directly in closed containers without sample prep. 09/17/2026