Dual-Target Nanoparticles Reprogram Macrophages and Improve Survival in Experimental Sepsis in ssalimpour

Researchers developed glutathione-responsive EONPs that co-deliver STING and DHODH inhibitors to reprogram macrophage inflammatory metabolism in experimental sepsis. In mouse models, the treatment reduced inflammation and organ injury, improved short-term survival, and altered gut microbial metabolism, with 5-HIAA contributing to the immune response. 10/26/2026

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Researchers developed diimmonium DB·2X nano-agents that support photoacoustic imaging at 1700 nm, with DB·2TFSI showing strong performance in preclinical imaging experiments. In mouse models, 1700 nm imaging reduced endogenous background interference and improved signal-to-background ratios compared with 1064 nm, supporting further investigation of NIR-IIb photoacoustic contrast agents. 10/26/2026

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Metallic materials used in extremely cold environments must maintain high strength, ductility and fracture toughness to support applications in aerospace, clean energy, superconducting systems and deep-space exploration. ... 10/24/2026

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Researchers at AIST have demonstrated the synthesis of nanoporous carbonaceous materials and carbonaceous materials with layered nanostructures through a simple process involving the chemical modification of common sugars ... 10/24/2026

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Researchers at Umea university thought gold particles would make electronic components emit more light. Instead, they discovered an unexpected effect that could be important for the future of organic electronics. 10/23/2026

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Molecular machines are regarded as the next step in miniaturization. Their models can be found in living cells, where molecular motors convert energy and generate movement. Scientists have been working for decades to artificially ... 10/23/2026

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After earning bachelor's and Ph.D. degrees in bioengineering with a focus on molecular biology, Will White, a postdoctoral scholar in the Department of Computer Science at Tufts, was pretty certain his future research would ... 10/23/2026

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This book addresses the critical need for innovative nanofibers and advanced processing techniques in electrospinning, establishing it as an... 10/23/2026

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Researchers developed a rapid, one-pot method that used sunlight and a commercial vincristine formulation to form gold nanoparticles within five minutes without separate reducing or stabilizing agents. The particles retained vincristine’s antiproliferative activity against Colo-205 colon cancer cells and showed greater DPPH radical scavenging than free vincristine at several tested concentrations, while questions about drug photostability, release, stability, and in vivo performance remain. 10/22/2026

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Researchers engineered hybrid strontium sulfite nanoparticle-modified lipid nanoparticles to deliver p53 mRNA, producing higher reporter-gene expression, higher p53 transcript levels, and greater apoptosis in breast cancer cells than conventional LNPs. In mice, the p53 mRNA-loaded hybrid carrier slowed 4T1 tumor growth, although the study was small and preclinical, and the clearest biodistribution advantage appeared after PEGylation. 10/21/2026

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PI (Physik Instrumente) L.P., a leading provider of precision motion control and nanopositioning solutions, today announced the A-323, a planar air bearing scanner for semiconductor inspection, metrology and photonics applications that demand high throughput. 10/21/2026

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Nanotechnology could help crops withstand drought through nanoparticles, nanobubble irrigation, water-retaining hydrogels, and nanosensors, but challenges remain. 10/08/2026

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High-speed nanoindentation and EBSD techniques are employed to analyze self-annealed electroplated Cu, highlighting spatial variations in mechanical properties. 10/06/2026

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Researchers are exploring whether engineered nanocarriers can improve delivery of drugs, genes, and RNA-based therapies to specific lung cells while reducing unwanted effects elsewhere in the body. 09/29/2026

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Developing stretchable displays integrates quantum dot engineering and novel printing methods, addressing key challenges in performance and durability. 09/25/2026

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Silica aerogel is widely recognized for its exceptionally low thermal conductivity; however, its inherent fragility and high porosity limit direct... 09/17/2026

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NanoLabSizer revolutionizes nanoparticle sizing with SR-DLS, enabling fast, non-destructive measurements directly in closed containers without sample prep. 09/17/2026

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