Anti-CD44 Nanoplatform Targets Glioblastoma Cells With Dual Ferroptosis and Photothermal Therapy in ssalimpour

Salimpour Website |Researchers developed a carboxymethyl cellulose-based immunonanosystem containing cobalt-substituted magnetite nanoparticles and anti-CD44 antibodies to target glioblastoma cells through enzyodynamic ferroptosis and photothermal therapy. In 2D cell cultures and 3D gliomaspheres,

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Anti-CD44 Nanoplatform Targets Glioblastoma Cells With Dual Ferroptosis and Photothermal Therapy

Anti-CD44 Nanoplatform Targets Glioblastoma Cells With Dual Ferroptosis and Photothermal Therapy

Researchers developed a carboxymethyl cellulose-based immunonanosystem containing cobalt-substituted magnetite nanoparticles and anti-CD44 antibodies to target glioblastoma cells through enzyodynamic ferroptosis and photothermal therapy. In 2D cell cultures and 3D gliomaspheres, the system showed preferential activity against CD44-expressing glioblastoma cells, supporting further preclinical studies of its safety, delivery, and therapeutic performance.