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Anti-CD44 Nanoplatform Targets Glioblastoma Cells With Dual Ferroptosis and Photothermal Therapy |
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Researchers developed a carboxymethyl cellulose-based immunonanosystem containing cobalt-substituted magnetite nanoparticles and anti-CD44 antibodies to target glioblastoma cells through enzyodynamic ferroptosis and photothermal therapy. In 2D cell cultures and 3D gliomaspheres, the system showed preferential activity against CD44-expressing glioblastoma cells, supporting further preclinical studies of its safety, delivery, and therapeutic performance. |
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2026-10-30 Read more about this article in source |
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Researchers have created a molecular "cage" that keeps protein-degrading drug molecules inactive until they are exposed to low-energy red light. The technology, called RuPHOTACs, controls when and where these molecules become ... 10/30/2026
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Supercharged 'molecule highway' membrane that speeds water transport could transform industrial processing
New membrane technology delivering faster and more precise molecule separation could improve the efficiency and sustainability of energy-intensive industrial processes—from purifying chemicals and recovering valuable resources ... 10/30/2026
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Phys.Org more ...
Customizable nanoparticles show potential for delivering personalized cancer vaccines
A nanoscale particle with a unique structure, developed at MIT, holds potential as a customizable delivery vehicle for personalized cancer vaccines. The backbone of the vaccine is a modified, harmless bacteriophage called ... 10/30/2026
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Anti-CD44 Nanoplatform Targets Glioblastoma Cells With Dual Ferroptosis and Photothermal Therapy
Researchers developed a carboxymethyl cellulose-based immunonanosystem containing cobalt-substituted magnetite nanoparticles and anti-CD44 antibodies to target glioblastoma cells through enzyodynamic ferroptosis and photothermal therapy. In 2D cell cultures and 3D gliomaspheres, the system showed preferential activity against CD44-expressing glioblastoma cells, supporting further preclinical studies of its safety, delivery, and therapeutic performance. 10/30/2026
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6-DOF MagLev Systems for Advanced Packaging Introduced at SEMICON West 2026, New From PI
PI (Physik Instrumente) introduced several magnetic levitation motion technology demonstrators at SEMICON West 2026. The platforms combine contact-free positioning with active control of all six degrees of freedom, eliminating mechanical bearing contact, lubrication, and bearing wear. 10/30/2026
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Phys.Org more ...
Light-emitting nanoparticles help ultrasound direct gene editing to selected mouse brain regions
Scientists can now edit genes in precise locations deep in the brain and body without the use of invasive surgery or implants, thanks to new work from researchers at the Wu Tsai Neurosciences Institute. The team demonstrated ... 10/30/2026
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Phys.Org more ...
Nanoparticle properties shape protein coats that guide cell entry and immune evasion
A new study has revealed molecular rules governing how nanoparticles interact with biological systems, showing how their physicochemical properties shape protein corona (PC) formation and influence biological outcomes. The ... 10/30/2026
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Researchers showed that point-defect engineering can control how copper nanoparticles exsolve from perovskite oxides, influencing exsolution yield, particle size, nucleation density, and anchoring. The study also found that oxygen vacancies are consumed during exsolution and that lattice strain can eventually limit further nanoparticle formation. 10/29/2026
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Hybrid Immune-Cell Nanoparticles Reduce Inflammation and Bone Loss in Periodontitis
Researchers developed NMm@MINO, a minocycline-loaded gelatin nanoparticle coated with hybrid neutrophil–macrophage membranes to tackle bacterial infection, inflammation, and periodontal tissue damage. In laboratory and rat experiments, the platform killed bacteria, altered inflammatory responses, promoted osteogenesis-associated processes, suppressed osteoclast activity, and reduced alveolar bone loss. 10/28/2026
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Researchers used spark plasma sintering technology to deposit silver, zinc, and copper metal oxide nanoparticles directly onto thermoplastic starch/carboxymethyl cellulose films, then measured changes in mechanical strength, wettability, morphology, color, and thermal behavior. The treatment increased tensile strength and reduced surface wettability, with the results varying by metal and reflecting interactions between the deposited particles and polymer functional groups. 10/27/2026
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in Encyclopedia of Green Materials 10/27/2026
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Large amounts of waste crab shells are generated at seafood processing plants. The main component, chitin, can be mechanically processed into... 10/27/2026
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in Encyclopedia of Green Materials 10/27/2026
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This book addresses the critical need for innovative nanofibers and advanced processing techniques in electrospinning, establishing it as an... 10/23/2026
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Nanotechnology could help crops withstand drought through nanoparticles, nanobubble irrigation, water-retaining hydrogels, and nanosensors, but challenges remain. 10/08/2026
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Structure-Property Relationship of Electroplated Cu Film by Combining Electron Backscatter Diffraction (EBSD) and High-Speed Nanoindentation Techniques
High-speed nanoindentation and EBSD techniques are employed to analyze self-annealed electroplated Cu, highlighting spatial variations in mechanical properties. 10/06/2026
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Researchers are exploring whether engineered nanocarriers can improve delivery of drugs, genes, and RNA-based therapies to specific lung cells while reducing unwanted effects elsewhere in the body. 09/29/2026
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Developing stretchable displays integrates quantum dot engineering and novel printing methods, addressing key challenges in performance and durability. 09/25/2026
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Springer more ...
Thermal performance of multilayer silica aerogel-embedded PVDF-HFP nanofiber fabric
Silica aerogel is widely recognized for its exceptionally low thermal conductivity; however, its inherent fragility and high porosity limit direct... 09/17/2026
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NanoLabSizer revolutionizes nanoparticle sizing with SR-DLS, enabling fast, non-destructive measurements directly in closed containers without sample prep. 09/17/2026